The progressive development of gas flow ultrafine pulverizer

Chinese medicine as the gem of the Chinese nation is our eternal wealth, with the development of traditional Chinese medicine of traditional Chinese medicine (TCM) crushing demands also have more, small grinding machine type and function also more and more diversified, crushing mainly by mechanical force will bulk solid material into pieces or fine powder of the operation process, is in the process of traditional Chinese medicine pharmaceutical basic unit operations.

The purpose of comminution is to facilitate the leaching of active components and facilitate extraction. The tissue cells of Chinese medicinal materials are generally arranged tightly, and the cell wall is very thick. The solvent is not easy to penetrate and spread. After being crushed to a certain degree, the cells are broken, which is conducive to infiltration and accelerates the dissolution, gelatinization or elution of the effective ingredients. It is beneficial to the preparation of tablets and other dosage forms. The preparation of tablets, powder, nine agents, capsules and other commonly used agents, all need to use the appropriate particle size of powder raw materials and auxiliary materials, so crushing and sieving is the basic operation procedures for the preparation of some agents; Easy to adjust, help to improve the internal quality of the drug. Pulverized and sieved powder, generally approximately the same size of fine powder. This is not only conducive to uniform mixing, reducing the weight or content difference of a single preparation unit, but also beneficial to oral absorption or better play its adsorption and covering function; External application may reduce local mechanical irritation; Facilitate the rapid drying of fresh Chinese medicinal materials; Increase drug surface area, promote drug dissolution and absorption.

The crushing process is accomplished mainly by applying mechanical forces that partially break down the cohesion between the molecules of the material. In other words, mechanical methods are used to increase the surface area of drugs, that is, the process of converting mechanical energy into surface energy. Whether this transformation is complete directly affects the efficiency of crushing. Airflow crusher requirements are mainly crushing degree requirements. The degree of crushing refers to the fineness of the material after crushing, which is an important indicator to check the effect of crushing operation. It is inversely proportional to the average diameter of the material particles after crushing, that is, the smaller the particles of the material after crushing, the greater the degree of crushing. The degree of comminution generally depends on manufacturing requirements, medical use and the nature of the drug itself. Excessive comminution may not be useful, and attention should be paid to undesirable phenomena and problems that may result from the comminution process, such as thermal decomposition, adhesion, recoalescence and poor fluidity.

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